HoLEP

ホルミウムレーザー前立腺核出術(HoLEP)は、様々な大きさの前立腺に対して行われるBPH治療です。11-15

HoLEPでは核出した腺腫を膀胱内でモルセレーターを使用して除去します。

HoLEPは、AUAでもBPH治療法として推奨されています。そのメリットには、再手術率の低さと幅広い患者への適用性があります。11,16

JUAではHoLEPは、TURPやその他の治療法と比較し根治性が高いとされています。
HoLEPは、抗凝固剤の服用患者にも施行可能であり灌流液が生理食塩水の為、TUR症候群のリスクが殆どありません。

詳細ダウンロード

臨床情報、処置のビデオ、詳細なパンフレットなどを入手できます。

HoLEPを施行した6年後1

6年間でのQOL、Qmax Ml/sおよびIPSSの結果は、1年での結果と同等

HoLEPは合併症が少なく再手術率も低い1、2、3、7、8、9、10

ビデオ

泌尿器科用デバイス

参照

  1. Holmium Laser Enucleation of the Prostate; Results at 6 Years, Gilling PJ, Aho, TF, Frampton CM, et al. Eur Urol 2008 Apr:53(4):744-9
  2. Holmium Laser Enucleation of the Prostate Versus Open Prostatectomy for Prostates Greater Than 100 Grams; 5-Year Follow-up Results of a Randomized ClinicalTrial, Kuntz RM, Lehrich K, Ahvai S. Eur Urol 2008 Apr:53:160-168
  3. A Randomized Trial Comparing Holmium Laser Enucleation of the Prostate with Transurethral Resection of the Prostate for the Treatment of Bladder Outlet Obstruction, Secondary to Benign Prostatic Hyperplasia in Large Glands (40 to 200 grams), Tan AH, Gilling P, et al. J Urol (Oct. 2003) 170:1270-1274
  4. Randomized Comparison of Transurethral Electroresection and Holmium: YAG Laser Vaporization for Symptomatic Benign Prostatic Hyperplasia, Mottet N, Anidjar J, et al. J Endourol 1999 13:127-130 5 Holmium Laser Enucleation of the Prostate for Prostates of >125mL., Matlaga BR, Lingeman JE, et al. BJU International, 97:81-84, Jan 2006
  5. Holmium Laser Enucleation of the Prostate for Prostates of >125mL., Matlaga BR, Lingeman JE, et al. BJU International, 97:81-84, Jan 2006
  6. Holmium Laser Bladder Neck Incision vs. Holmium Enucleation of the Prostate as Outpatient Procedures for Prostates Less Than 40 Grams: A Randomized Trial, Aho, TF, Gilling P, et al. J Urol, 174, 210-214, Jul 2005
  7. KTP Laser versus transurethral resection: early results of a randomized trial Bouchier-Hayes DM, Anderson P, et al. J Endourol 2006 Vol 20 (8):580-585
  8. Photoselective potassium titanyl phosphate (KTP) laser vaporization vs. transurethral resection of the prostate for prostates larger than 70mL: a short-term prospective randomized trial Horasanli K, Silay M, et al. J Urol 2008 71:247-251
  9. Laser: A Novel Side-Firing Approach for Laser Vaporisation of the Human Prostate – Immediate Efficacy and 1 – Year Follow- Up Seitz M., Sroka, R., et al. Eur Urol 2007 June; 52 1717-1772
  10. Thulium Laser versus Standard Transurethral Resection of the Prostate: A Randomized Trial Xia, S. et al. European Urology 2006 Vol 53 382-390
  11. John Michalak, David Tzou, Joel Funk: HoLEP: the gold standard for the surgical management of BPH in the 21st Century Am J Clin Exp Urol 2015;3(1):36-42
  12. Ehab A. Elzayat, Enmar I. Habib, and Mostafa M. Elhilali: Holmium laser enucleation of the prostate: a size-independent new “gold standard” urology 66 (Supplement 5A), November 2005
  13. Gilling PJ et al, Long-term results of a randomized trial comparing holmium laser enucleation of the prostate and transurethral resection of the prostate: results at 7 years. BJU Int 2012; 109(3): 408-11.
  14. Elmansy H et al, Holmium Laser Enucleation Versus Photoselective Vaporization for Prostatic Adenoma Greater than 60 Ml: Preliminary Results of a Prospective, Randomized Clinical Trial. J Urol 2012; 188: 216-221.
  15. Ahyai S et al, Holmium Laser Enucleation versus Transurethral Resection of the Prostate: 3-Year Follow-Up Results of a Randomized Clinical Trial. Eur Urol 2007; 52(5):1456-63. 16. American Urological Association Guideline: Management of Benign Prostatic Hyperplasia (BPH), 2010.

PB-1004683 A  | PB-2007840 rev A